Viagra Malaysia is a prescription drug that’s used to treat erectile dysfunction. It increases blood flow to the penis, which helps you get and keep an erection during sexual activity.
In some people, Viagra can cause serious side effects. Call your doctor right away if you have severe side effects.
Some medications, foods, or drinks can affect how well Viagra works. Tell your doctor and pharmacist about all the drugs, including prescription and over-the-counter drugs, vitamins, and supplements you take.
PDE5 Inhibitor
Phosphodiesterase type-5 inhibitors (PDE5i) remain the standard pharmacologic treatment for erectile dysfunction (ED). With more brand and generic options coming to market, pharmacists–along with their patients–will benefit from an understanding of the subtle differences between oral therapies.
Originally developed for cardiovascular health issues, these medications improve blood flow to certain tissues by inhibiting the activity of an enzyme found in the smooth muscle cells of blood vessels. The most commonly available drugs include Viagra(r) (sildenafil), Cialis(r) (tadalafil), Levitra(r) (vardenafil), and Stendra(r) (avanafil).
When the parasympathetic nervous system is activated during sexual arousal, it prompts nitric oxide release from endothelial cells in the penis. This nitric oxide, in turn, initiates a cascade of events that lead to corporal smooth muscle relaxation and penile erection. One of the key events in this process involves cyclic GMP (cGMP), which plays a critical role in the initiation phase by activating cGMP-dependent protein kinase and triggering a series of downstream events that culminate in full erection. PDE5i inhibits the enzyme that breaks down cGMP to preserve its effectiveness and enhance the effects of nitric oxide in the penis.
The same mechanism also works to alleviate pulmonary arterial hypertension (PAH). Upon binding to PDE5 isoforms, PDE5i cause a dramatic increase in pulmonary vasodilation by enhancing the action of mediators that induce vasodilation such as nitric oxide and guanylyl cyclase.
All oral PDE5i are designed to be taken on an empty stomach, though some may require a longer period before the drug takes effect. Patients should avoid alcohol, as it will decrease the effectiveness of the medication and can also worsen the side effects.
Oral PDE5i are generally well tolerated. Common side effects can include headache, flushing, back pain, and dyspepsia. More serious side effects that should be reported to a physician immediately include chest pain, nausea, vomiting, dark urine, and liver damage.
Blood Flow Increaser
A prescription drug called Viagra (sildenafil) helps men with erectile dysfunction (ED) get and keep an erection that’s firm enough to have sexual intercourse. ED is an extremely common condition, and it’s estimated that 30 million people in the United States suffer from it. The drug works by improving blood flow to the penis. Known as the little blue pill, it’s one of the most popular drugs for treating ED on the market today.
The drug’s mechanism of action involves inhibiting the enzyme PDE-5. During sexual stimulation, the brain sends signals to the penis that cause it to release a chemical called cGMP. This relaxes the muscle cells in the erectile tissue of the penis, which causes blood to flow into the area and create an erection. However, PDE-5 breaks down cGMP and makes it hard to maintain an erection. Viagra works by blocking the effects of PDE-5, which allows cGMP to remain in circulation and improves blood flow into the penis.
In addition to treating ED, the drug also can improve a man’s sex drive. It can help him feel more energized and confident, which can lead to an improvement in his performance during sex. It can also reduce the duration of a painful erection.
Viagra is not suitable for everyone, and you should not take it if you have certain physical conditions or medical problems. For example, if you have a disease that affects the way your penis grows or a medical problem that causes your penis to bend, such as Peyronie’s disease, you shouldn’t take the medication. It can also cause a rare side effect called priapism, which is a long-lasting and sometimes painful erection.
Mild side effects of Viagra aren’t uncommon, and many go away within a few days or a couple of weeks. If they become bothersome, talk to your doctor or pharmacist for tips on how to deal with them. In some cases, a doctor may recommend that you skip doses or take the medication less often. The FDA tracks reports of side effects from patients taking the medication. If you have a serious side effect, call 911 or your local emergency number immediately.
Stimulant
Kamagra Malaysia is a pill that helps men with erectile dysfunction (ED). It works by increasing blood flow to the penis when sexual stimulation occurs. It can also help maintain an erection after sexual activity has ended. Viagra is in a class of drugs called PDE5 inhibitors. Its active ingredient is sildenafil citrate.
Before taking Viagra, talk with your doctor if you have any medical conditions or have had surgery or a stroke. Your doctor will decide if it is safe for you to take Viagra. If you have a history of heart disease, high blood pressure, or liver or kidney problems, you may need to take a lower dose. If you have a bleeding disorder, such as hemophilia or hepatitis C, you should also avoid Viagra.
The drug can cause side effects, such as headaches, flushing, indigestion, dizziness, or a rapid heartbeat. These side effects can usually be eased by lying down or avoiding alcohol. If you have a blood cell problem, such as sickle cell anemia or multiple myeloma, you should also not take Viagra. This is because it could increase your risk of priapism, a long-lasting and painful erection that doesn’t go away.
You should also not take Viagra if you are taking nitrate medications. These include prescription drugs, such as nitroglycerin used to treat chest pain, and illicit drugs such as amyl nitrate. Viagra can also interact with some antidepressants, such as amitriptyline and citalopram.
In most males, Viagra begins to work within an hour after it is taken. The effects can last up to 8 hours. But you should not attempt to get an erection for more than 4 hours because this can cause permanent damage to the penis.
If you are having trouble getting an erection while on Viagra, try sexual stimulation, such as foreplay or oral sex. You should also stop drinking alcohol because it can make Viagra less effective or reduce how long the effects last. If you still aren’t having success, ask your doctor for advice. They can recommend other treatments for ED, such as aphrodisiacs or other medications that are more likely to work with your body.
Aphrodisiac
Aphrodisiacs are substances that arouse sexual desire. They have been used for centuries in a variety of cultures. They can include foods such as chocolate and oysters, herbs such as maca and ginseng, and drugs such as Viagra.
The drug improves blood flow into the penis when you are sexually aroused, which helps you to have and keep an erection. It does this by blocking the action of PDE5, which normally breaks down cGMP in the penis. This increases the amount of cGMP in your body, which makes it easier to have an erection.
In clinical studies, Viagra has been shown to help men have and keep erections that allow for successful sex. However, it does not increase a man’s libido. This is because aphrodisiacs work by stimulating the brain’s receptors for sex hormones. Viagra is not a sex drug, but it can make you more likely to want sex and to have sex successfully.
If you have a blood cell condition that affects your blood vessels, such as sickle cell anemia, you may be at a higher risk for priapism (long-lasting erections). If this happens, call your doctor right away. You should also tell your doctor if you have any conditions that cause an abnormal shape of your penis, such as Peyronie’s disease.
Viagra can cause serious side effects, such as headache, rash, nausea, dizziness, and diarrhea. Some of these side effects can be dangerous or even life-threatening. You should tell your doctor if you have any of these side effects, especially if they are severe or don’t go away.
Always talk to your doctor before taking any aphrodisiacs. They can tell you if they are safe for you and whether they will interact with any other medications or supplements that you are taking. You should also talk to your doctor about any problems you have with sex, including reduced libido. Sometimes these symptoms can be a sign of a medical problem.